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Corpus uteri - Ladies

Rates per 100,000 inhabitants

Table 1: Incidence: frequencies, crude and standardized rates per year

Incidence		1999	2000	2001	2002	2003	2004	2005	2006	1999‑2006
Count		175	179	173	197	169	214	197	196	1500
Crude rate		25.7	26.5	25.7	29.5	25.4	31.7	28.7	28.4	27.7 (26.3‑29.1)
Standardized rate	Italy 2001	20.8	21.3	20.5	22.8	19.7	24.6	23.3	23.4	22.0 (20.9‑23.2)
Standardized rate	Europe	16.3	16.7	15.9	17.1	14.9	18.7	18.5	18.5	17.1 (16.2‑18.0)
Standardized rate	World	11.7	11.9	11.3	11.9	10.7	13.1	13.4	13.4	12.2 (11.5‑12.9)

Table 2: Mortality: frequencies, crude and standardized rates per year

Mortality		1999	2000	2001	2002	2003	2004	2005	2006	1999‑2006
Count		11	18	19	20	19	10	21	18	136
Crude rate		1.6	2.7	2.8	3.0	2.9	1.5	3.1	2.6	2.5 (2.1‑3.0)
Standardized rate	Italy 2001	1.2	1.9	2.1	2.2	1.9	1.0	2.2	1.9	1.8 (1.5‑2.1)
Standardized rate	Europe	0.7	1.1	1.4	1.4	1.1	0.6	1.2	1.3	1.1 (0.9‑1.3)
Standardized rate	World	0.4	0.7	1.0	0.9	0.7	0.4	0.8	0.9	0.7 (0.6‑0.9)

Table 3: Register quality indicators per year

Indicator	1999	2000	2001	2002	2003	2004	2005	2006	1999‑2006
Mortality/Incidence ratio (%)	5.8	8.9	10.2	9.6	9.6	4.1	9.4	8.1	8.2
Cito-histologically confirmed (%)	96.6	99.4	97.1	97.5	98.2	98.6	97.5	93.9	97.3
Death certificate only - DCO (%)	0.0	0.0	0.0	0.5	0.0	0.0	0.5	0.0	0.1

Table 4: Comparison of Italian Registries mean prevalence by macro-areas

Graf 04

_	Milan	North West	North East	Centre	South	Italy
Incidence	17.6	17.6	17.9	19.1	16.7	17.9
Mortality	1.1	1.4	1.2	0.9	1.0	1.1

Table 5: Basis of diagnosis per period

_	1999‑2002	%	2003‑2006	%	1999‑2006	%
Histological	703	97.1	750	96.7	1453	96.9
Citological	4	0.6	3	0.4	7	0.5
Clinical	16	2.2	21	2.7	37	2.5
DCO	1	0.1	1	0.1	2	0.1

Table 6: More frequent morphologies

Morphology	N	%
Endometrioid adenocarcinoma, NOS	538	71.4
Adenocarcinoma, NOS	115	15.3
Leiomyosarcoma, NOS	15	2.0
Endometrioid adenocarcinoma, secretory variant	12	1.6
M³llerian mixed tumour (C54._)	10	1.3
Clear cell adenocarcinoma, NOS	9	1.2

Table 7: Age distribution of rates

Graf 07

Age groups	Incidence	Mortality
0	0.0	0.0
1-4	0.0	0.0
5-9	0.0	0.0
10-14	0.0	0.0
15-19	0.0	0.0
20-24	0.0	0.0
25-29	1.3	0.0
30-34	1.4	0.0
35-39	3.6	0.0
40-44	12.0	0.0
45-49	18.7	0.6
50-54	25.8	0.0
55-59	55.2	1.1
60-64	66.9	1.6
65-69	63.0	5.2
70-74	56.9	9.7
75-79	65.1	8.0
80-84	64.1	7.8
85+	38.7	13.9

Table 8: Temporal trends of rates

Graf 08

Year	Mortality	Incidence
1999	0.7	16.3
2000	1.1	16.7
2001	1.4	15.9
2002	1.4	17.1
2003	1.1	14.9
2004	0.6	18.7
2005	1.2	18.5
2006	1.3	18.5

Table 10: Comparison of Italian Registries mean prevalence by macro-areas

Graf 10

Years since diagnosis	Italy	South	Centre	North East	North West	Milan
0-2	45.6	36.2	46.8	46.0	50.5	54.8
2-5	56.0	39.3	59.0	58.4	61.8	59.4
5-10	73.4	52.4	80.5	74.0	81.7	84.7
10-15	56.4	37.7	58.6	61.1	60.8	62.9
15-20	39.7	26.5	41.7	40.1	46.8	45.4
>20	56.4	35.0	59.5	58.5	65.6	65.9

Table 11: 5 years relative survival by macro-areas

Graf 11

Area	Relative survival (95% CI)
Milan	78.4 (75.2‑81.7)
North West	77.5 (75.8‑79.2)
North Est	76.2 (74.7‑77.7)
Centre	75.7 (73.1‑78.1)
South	71.4 (68.6‑74.1)
Italy	76.0 (75.0‑76.9)

Table 12: Relative survival by age since diagnosis

Age class	0	1	2	3	4	5
15-44	100.00	96.40	94.60	92.80	90.90	90.90
45-59	100.00	96.40	93.90	91.00	88.70	88.10
60-74	100.00	94.20	89.50	86.30	83.60	81.50
75+	100.00	82.00	74.60	69.90	68.70	67.50

Table 13: 5 years relative survival by biennium of incidence

Years since diagnosis	1999‑2000	2001‑2002	2003‑2004	2005‑2006
1	90.4	89.6	93.5	93
2	85.4	83.8	91.4	86.7
3	82.5	80.2	85.8	84.5
4	79.8	78	84.9	82
5	78.6	75.7	81.6	81.2

Table 14: Rates distribution by deprivation index

‑	1	2	3	4	5
Incidence	25.1	29.6	29.8	26.3	27.4
Mortality	1.7	1.5	3.5	2.1	2.8

Table 15: Relative survival by deprivation index

Years since diagnosis	Most deprived	Most affluent
0	100.0	100.0
1	94.9	93.0
2	91.0	89.2
3	84.9	86.4
4	84.5	84.2
5	81.8	83.1