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Skin (but melanoma) - Ladies

Rates per 100,000 inhabitants

Table 1: Incidence: frequencies, crude and standardized rates per year

Incidence		1999	2000	2001	2002	2003	2004	2005	2006	1999‑2006
Count		478	552	615	663	610	609	618	628	4773
Crude rate		70.3	81.7	91.4	99.2	91.7	90.2	90.0	91.0	88.2 (85.7‑90.7)
Standardized rate	Italy 2001	55.0	63.4	71.3	75.6	70.0	70.0	69.3	70.6	68.2 (66.2‑70.2)
Standardized rate	Europe	39.6	45.3	51.4	54.5	51.6	51.8	50.4	51.8	49.6 (48.0‑51.2)
Standardized rate	World	27.5	31.6	36.4	38.1	37.0	37.5	36.2	37.1	35.2 (34.0‑36.4)

Table 2: Mortality: frequencies, crude and standardized rates per year

Mortality		1999	2000	2001	2002	2003	2004	2005	2006	1999‑2006
Count		5	2	4	5	4	5	5	7	37
Crude rate		0.7	0.3	0.6	0.7	0.6	0.7	0.7	1.0	0.7 (0.5‑0.9)
Standardized rate	Italy 2001	0.4	0.2	0.4	0.4	0.3	0.4	0.4	0.7	0.4 (0.3‑0.6)
Standardized rate	Europe	0.2	0.1	0.2	0.2	0.2	0.2	0.3	0.4	0.2 (0.2‑0.4)
Standardized rate	World	0.1	0.1	0.1	0.1	0.1	0.1	0.2	0.3	0.1 (0.1‑0.2)

Table 3: Register quality indicators per year

Indicator	1999	2000	2001	2002	2003	2004	2005	2006	1999‑2006
Mortality/Incidence ratio (%)	0.7	0.3	0.6	0.5	0.4	0.6	0.6	1.0	0.6
Cito-histologically confirmed (%)	95.4	97.5	97.1	99.1	47.7	38.9	39.3	30.4	67.3
Death certificate only - DCO (%)	0.2	0.4	0.0	0.3	0.2	0.0	0.0	0.0	0.1

Table 4: Comparison of Italian Registries mean prevalence by macro-areas

Graf 04

_	Milan	North West	North East	Centre	South	Italy
Incidence	51.4	31.8	64.7	54.2	34.8	53.6
Mortality	0.3

Table 5: Basis of diagnosis per period

_	1999‑2002	%	2003‑2006	%	1999‑2006	%
Histological	2248	97.4	962	39.0	3210	67.3
Citological	0	0.0	0	0.0	0	0.0
Clinical	55	2.4	1501	60.9	1556	32.6
DCO	5	0.2	1	0.0	6	0.1

Table 6: More frequent morphologies

Morphology	N	%
Basal cell carcinoma, NOS (C44._)	655	68.1
Squamous cell carcinoma, NOS	92	9.6
Superficial spreading melanoma (C44._)	51	5.3
Multifocal superficial basal cell carcinoma (C44._)	41	4.3
Malignant melanoma, NOS (except juvenile melanoma M87700)	23	2.4
Dermatofibrosarcoma, NOS (C44._)	15	1.6

Table 7: Age distribution of rates

Graf 07

Age groups	Incidence	Mortality
0	0.0	0.0
1-4	0.0	0.0
5-9	1.1	0.0
10-14	1.1	0.0
15-19	2.4	0.0
20-24	4.0	0.0
25-29	11.5	0.0
30-34	12.5	0.0
35-39	31.5	0.0
40-44	39.6	0.0
45-49	52.5	0.0
50-54	75.1	0.0
55-59	86.0	1.1
60-64	142.7	0.5
65-69	171.4	0.0
70-74	214.6	0.6
75-79	209.1	0.0
80-84	291.0	4.3
85+	254.1	11.9

Table 8: Temporal trends of rates

Graf 08

Year	Mortality	Incidence
1999	0.2	39.6
2000	0.1	45.3
2001	0.2	51.4
2002	0.2	54.5
2003	0.2	51.6
2004	0.2	51.8
2005	0.3	50.4
2006	0.4	51.8

Table 11: 5 years relative survival by macro-areas

Graf 11

Area	Relative survival (95% CI)
Milan	98.7 (98.0‑99.4)
North West	NA
North Est	NA
Centre	NA
South	NA
Italy	NA

Table 12: Relative survival by age since diagnosis

Age class	0	1	2	3	4	5
15-44	100.00	99.70	99.50	99.20	98.20	97.90
45-59	100.00	99.50	99.20	98.70	98.20	98.20
60-74	100.00	99.60	99.20	99.00	98.60	98.60
75+	100.00	100.00	100.00	99.40	99.40	99.40

Table 13: 5 years relative survival by biennium of incidence

Years since diagnosis	1999‑2000	2001‑2002	2003‑2004	2005‑2006
1	99.9	100	100	99.4
2	99.8	99.2	100	99.1
3	99.5	98.3	99.9	98.6
4	99.5	98.1	99.6	98.6
5	99.5	98.1	99.6	98.6

Table 14: Rates distribution by deprivation index

‑	1	2	3	4	5
Incidence	99.1	95.1	91.4	80.2	73.4
Mortality	0.7	0.5	1.3	0.4	0.3

Table 15: Relative survival by deprivation index

Years since diagnosis	Most deprived	Most affluent
0	100.0	100.0
1	98.3	100.0
2	97.2	100.0
3	95.5	99.4
4	94.8	99.4
5	94.8	98.9