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Trachea, bronchus and lung - Ladies

Rates per 100,000 inhabitants

Table 1: Incidence: frequencies, crude and standardized rates per year

Incidence		1999	2000	2001	2002	2003	2004	2005	2006	1999‑2006
Count		346	295	337	354	330	381	364	348	2755
Crude rate		50.9	43.7	50.1	52.9	49.6	56.5	53.0	50.4	50.9 (49.0‑52.8)
Standardized rate	Italy 2001	39.8	33.8	37.6	39.5	36.6	41.9	39.7	37.7	38.3 (36.9‑39.8)
Standardized rate	Europe	27.5	23.5	25.3	27.0	25.2	29.3	27.6	26.6	26.4 (25.4‑27.6)
Standardized rate	World	18.7	16.1	17.2	18.1	16.8	20.1	18.7	18.1	17.9 (17.1‑18.8)

Table 2: Mortality: frequencies, crude and standardized rates per year

Mortality		1999	2000	2001	2002	2003	2004	2005	2006	1999‑2006
Count		258	286	283	304	305	287	311	294	2328
Crude rate		37.9	42.3	42.0	45.5	45.8	42.5	45.3	42.6	43.0 (41.3‑44.8)
Standardized rate	Italy 2001	29.2	31.9	31.4	32.9	33.0	30.6	32.0	31.3	31.5 (30.2‑32.8)
Standardized rate	Europe	19.2	20.9	20.8	21.5	21.9	20.3	20.6	21.2	20.8 (19.8‑21.7)
Standardized rate	World	12.7	13.9	13.7	14.1	14.5	13.4	13.4	14.2	13.7 (13.1‑14.4)

Table 3: Register quality indicators per year

Indicator	1999	2000	2001	2002	2003	2004	2005	2006	1999‑2006
Mortality/Incidence ratio (%)	73.4	94.4	83.5	83.3	90.2	73.0	80.6	83.0	82.2
Cito-histologically confirmed (%)	58.4	65.1	61.7	67.5	69.4	70.6	66.2	68.7	66.0
Death certificate only - DCO (%)	3.8	4.8	5.6	5.9	6.1	3.7	5.5	5.8	5.1

Table 4: Comparison of Italian Registries mean prevalence by macro-areas

Graf 04

_	Milan	North West	North East	Centre	South	Italy
Incidence	27.1	19.0	19.4	17.8	11.7	17.8
Mortality	20.9	15.1	15.1	13.8	9.9	14.0

Table 5: Basis of diagnosis per period

_	1999‑2002	%	2003‑2006	%	1999‑2006	%
Histological	648	48.7	750	52.7	1398	50.7
Citological	193	14.5	228	16.0	421	15.3
Clinical	424	31.8	360	25.3	784	28.5
DCO	67	5.0	74	5.2	141	5.1

Table 6: More frequent morphologies

Morphology	N	%
Adenocarcinoma, NOS	345	35.3
Non-small cell carcinoma (C34._)	115	11.8
Squamous cell carcinoma, NOS	106	10.8
Small cell carcinoma, NOS	84	8.6
Carcinoma, NOS	41	4.2
Oat cell carcinoma (C34._)	33	3.4

Table 7: Age distribution of rates

Graf 07

Age groups	Incidence	Mortality
0	0.0	0.0
1-4	0.0	0.0
5-9	0.0	0.0
10-14	0.0	0.0
15-19	0.0	0.0
20-24	4.0	2.0
25-29	0.0	0.0
30-34	0.5	0.5
35-39	5.4	1.8
40-44	8.0	4.0
45-49	22.2	16.3
50-54	43.2	26.4
55-59	60.0	37.1
60-64	58.6	45.5
65-69	94.3	74.0
70-74	140.1	107.6
75-79	171.3	156.0
80-84	190.5	194.9
85+	148.9	160.8

Table 8: Temporal trends of rates

Graf 08

Year	Mortality	Incidence
1999	19.2	27.5
2000	20.9	23.5
2001	20.8	25.3
2002	21.5	27.0
2003	21.9	25.2
2004	20.3	29.3
2005	20.6	27.6
2006	21.2	26.6

Table 10: Comparison of Italian Registries mean prevalence by macro-areas

Graf 10

Years since diagnosis	Italy	South	Centre	North East	North West	Milan
0-2	27.9	15.4	26.6	29.1	35.6	52.9
2-5	15.4	7.6	15.0	16.6	18.6	24.8
5-10	12.6	6.8	12.8	12.6	15.9	23.0
10-15	6.5	2.4	7.3	8.6	6.1	9.4
15-20	3.0	1.1	3.9	2.9	3.9	4.5
>20	2.3	1.0	2.3	2.4	3.0	4.2

Table 11: 5 years relative survival by macro-areas

Graf 11

Area	Relative survival (95% CI)
Milan	18.0 (15.8‑20.2)
North West	16.9 (15.7‑18.2)
North Est	17.3 (16.2‑18.4)
Centre	18.6 (16.6‑20.6)
South	15.1 (12.9‑17.4)
Italy	17.1 (16.4‑17.9)

Table 12: Relative survival by age since diagnosis

Age class	0	1	2	3	4	5
15-44	100.00	67.10	40.30	35.30	31.80	31.80
45-59	100.00	58.40	39.80	33.10	28.50	25.60
60-74	100.00	50.80	33.10	27.00	23.20	20.60
75+	100.00	34.00	21.30	14.90	12.80	11.70

Table 13: 5 years relative survival by biennium of incidence

Years since diagnosis	1999‑2000	2001‑2002	2003‑2004	2005‑2006
1	44.7	43.4	46.4	47.7
2	27.9	26	28.8	35.1
3	21.5	20.6	22.4	28.5
4	18.6	17.8	18.9	24.4
5	16.7	15.3	16.5	22.9

Table 14: Rates distribution by deprivation index

‑	1	2	3	4	5
Incidence	49.7	55.1	44.4	48.6	55.1
Mortality	41.6	46.5	38.2	35.8	50.1

Table 15: Relative survival by deprivation index

Years since diagnosis	Most deprived	Most affluent
0	100.0	100.0
1	41.3	49.1
2	27.2	36.4
3	20.3	30.0
4	17.8	27.0
5	16.3	24.6